# Used 2021 Mercedes-Benz CLS 450 prices

> The average asking price for a used 2021 Mercedes-Benz CLS 450 is $38,846, with 45,701 miles on average, across 28 cars for sale at U.S. dealers as of Nov 10, 2026.

Data as of Nov 14, 2026 · [ottoquest.com](https://ottoquest.com/models/mercedes-benz-cls450/2021) · [all Mercedes-Benz CLS 450 model years](https://ottoquest.com/models/mercedes-benz-cls450.md)

- Average asking price: $38,846 (median $39,906)
- Average miles: 45,701
- For sale now: 28
- Average days listed: 37 (of 25 with a listing date)

## 2021 Mercedes-Benz CLS 450 prices by state

States with 5 or more cars for sale.

| State | Average asking | Average miles | For sale | Days listed |
| --- | ---: | ---: | ---: | ---: |
| Florida | $37,650 | 53,525 | 6 | 35 |

## Other Mercedes-Benz CLS 450 years

| Year | Average asking | Miles | For sale |
| --- | ---: | ---: | ---: |
| [2023](https://ottoquest.com/models/mercedes-benz-cls450/2023.md) | $51,554 | 27,060 | 79 |
| [2022](https://ottoquest.com/models/mercedes-benz-cls450/2022.md) | $43,432 | 34,984 | 31 |
| **2021** | $38,846 | 45,701 | 28 |
| [2020](https://ottoquest.com/models/mercedes-benz-cls450/2020.md) | $32,669 | 58,113 | 40 |
| [2019](https://ottoquest.com/models/mercedes-benz-cls450/2019.md) | $28,816 | 64,866 | 86 |

## Recalls · 8

NHTSA, this model year.

- ELECTRICAL SYSTEM:WIRING (Feb 9, 2024): Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 CLS450, E450, E450 All-Terrain, AMG E53, AMG GT43, AMG GT53, and 2021 AMG CLS53 vehicles.  The 48-volt ground cable connection located in the engine compartment may not be tightened properly and may result in the ground cable overheating.
- ELECTRICAL SYSTEM:12V/24V/48V BATTERY (Sep 30, 2022): Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2022 CLS450 Coupe and AMG E53, 2019-2021 AMG CLS53 Coupe, and 2021-2022 E450 vehicles.  The 12-Volt battery in the trunk may not be properly secured, which, in the event of a crash, can cause electrical connection failure, disabling various safety features including, emergency call (eCall) system, electric seat adjustment, hazard warning lights, and automatic door locks.
- ELECTRICAL SYSTEM:SOFTWARE (May 20, 2022): Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles.  Please refer to MBUSA's recall report for specific vehicle model details.  An error in the communication module's SIM card software can cause a mobile network connection failure, disabling the emergency call (eCall) system.
- AIR BAGS:SENSOR:SIDE IMPACT (Jul 12, 2021): Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 CLS450, AMG E53, AMG CLS53, E350, E450, AMG GT43, AMG GT53, 2020 S450, S560, G550, AMG GLC63, 2020-2021 GLC300, and AMG G63 vehicles.  The side crash sensor connectors may come loose, which could delay the activation of air bags and seatbelts during a side impact crash.
- SEAT BELTS:REAR/OTHER:RETRACTOR (Jun 25, 2021): Mercedes-Benz, LLC (MBUSA) is recalling certain 2021 G550, AMG G63, E350, E450, AMG CLS53, AMG E53, AMG GT43, AMG GT53, AMG GT63, 2021-2022 CLS450, and AMG E63 vehicles.  The rear seat belt automatic locking retractors may deactivate early, which can prevent the child restraint system from securing properly.  As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 208, "Occupant Crash Protection."
- ELECTRICAL SYSTEM:SOFTWARE (May 14, 2021): Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2021 CLA-Class, GLE/GLS-Class, A-Class, E-Class, E-Class Coupe and Convertible, GLA/GLB-Class, GLC-Class, CLS-Class, and AMG GT-Class 4-door Coupe vehicles.  Please refer to MBUSA's recall report for specific vehicle model details.  The MBUX multimedia system software may cause the display to remain black, or reboot after startup.  This could result in the rearview camera image not displaying properly.  As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard (FMVSS) number 111, "Rear Visibility."

## Used 2021 Mercedes-Benz CLS 450 prices: common questions

### What is a fair price for a used 2021 Mercedes-Benz CLS 450?

Used 2021 Mercedes-Benz CLS 450s for sale at U.S. dealers ask $38,846 on average (half ask less than $39,906), across 28 cars. The cars for sale have 45,701 miles on average: one with fewer miles is worth more, and one with more is worth less. To check one car's price against cars of its trim and mileage, enter its VIN in OttoQuest's free Deal Check.

### How long are used 2021 Mercedes-Benz CLS 450s for sale?

The 25 for sale with a listing date have been listed 37 days on average. A car listed much longer than that, or one whose price has already been cut, usually leaves more room to negotiate.

### How does the 2021 Mercedes-Benz CLS 450 compare with the 2020 and 2022?

The 2021 asks $38,846 on average with 45,701 miles; the 2020 asks $32,669 with 58,113 miles, and the 2022 asks $43,432 with 34,984 miles.

### Does the 2021 Mercedes-Benz CLS 450 have recalls?

NHTSA lists 8 safety recall campaigns that cover the 2021 Mercedes-Benz CLS 450. Repairs are free at a dealer of the make; check a car's VIN with NHTSA before you buy to see whether its recalls were fixed.

## More

- Check one car's price: https://ottoquest.com/deal-check.md?vin=<VIN>&price=<price>&mileage=<miles> (markdown; the page is https://ottoquest.com/deal-check)
- Value a car by model, trim, year and mileage: https://ottoquest.com/value
- Free alerts for new listings and price drops: https://ottoquest.com/deals

Used and certified cars for sale at U.S. dealers, each car counted once. Days listed are the dealer's own days on market where they publish it. Price moves compare the same cars at both ends of the window.

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OttoQuest · [this page](https://ottoquest.com/models/mercedes-benz-cls450/2021). Prices are asking prices of cars for sale in the U.S. and recorded sold prices; a guide to the price, not to a car's condition.
