# Used 2021 Mercedes-Benz E 350 prices

> The average asking price for a used 2021 Mercedes-Benz E 350 is $29,391, with 49,918 miles on average, across 122 cars for sale at U.S. dealers as of Nov 10, 2026.

Data as of Nov 14, 2026 · [ottoquest.com](https://ottoquest.com/models/mercedes-benz-e350/2021) · [all Mercedes-Benz E 350 model years](https://ottoquest.com/models/mercedes-benz-e350.md)

- Average asking price: $29,391 (median $28,974)
- Average miles: 49,918
- For sale now: 122
- Average days listed: 63 (of 122 with a listing date)

## 2021 Mercedes-Benz E 350 prices by state

States with 5 or more cars for sale.

| State | Average asking | Average miles | For sale | Days listed |
| --- | ---: | ---: | ---: | ---: |
| California | $27,849 | 55,148 | 19 | 41 |
| Florida | $29,206 | 42,901 | 14 | 47 |
| Texas | $26,905 | 55,989 | 14 | 60 |
| Georgia | $28,982 | 50,599 | 11 | 81 |
| Illinois | $29,852 | 54,382 | 7 | 54 |
| New York | $28,502 | 47,296 | 7 | 54 |
| Ohio | $27,034 | 74,054 | 6 | 55 |
| Virginia | $24,708 | 58,733 | 5 | 96 |
| New Jersey | $34,504 | 33,347 | 5 | 111 |

## Other Mercedes-Benz E 350 years

| Year | Average asking | Miles | For sale |
| --- | ---: | ---: | ---: |
| [2027](https://ottoquest.com/models/mercedes-benz-e350/2027.md) | $73,202 | 494 | 25 |
| [2026](https://ottoquest.com/models/mercedes-benz-e350/2026.md) | $64,623 | 5,263 | 343 |
| [2025](https://ottoquest.com/models/mercedes-benz-e350/2025.md) | $50,558 | 17,582 | 119 |
| [2024](https://ottoquest.com/models/mercedes-benz-e350/2024.md) | $50,596 | 19,158 | 125 |
| [2023](https://ottoquest.com/models/mercedes-benz-e350/2023.md) | $40,603 | 29,568 | 403 |
| [2022](https://ottoquest.com/models/mercedes-benz-e350/2022.md) | $33,406 | 41,196 | 125 |
| **2021** | $29,391 | 49,918 | 122 |
| [2020](https://ottoquest.com/models/mercedes-benz-e350/2020.md) | $24,863 | 57,574 | 127 |
| [2016](https://ottoquest.com/models/mercedes-benz-e350/2016.md) | $14,097 | 103,019 | 116 |
| [2015](https://ottoquest.com/models/mercedes-benz-e350/2015.md) | $13,562 | 102,227 | 63 |
| [2014](https://ottoquest.com/models/mercedes-benz-e350/2014.md) | $12,376 | 104,752 | 294 |
| [2013](https://ottoquest.com/models/mercedes-benz-e350/2013.md) | $11,423 | 100,663 | 122 |
| [2012](https://ottoquest.com/models/mercedes-benz-e350/2012.md) | $11,380 | 103,409 | 97 |
| [2011](https://ottoquest.com/models/mercedes-benz-e350/2011.md) | $9,598 | 105,774 | 100 |
| [2010](https://ottoquest.com/models/mercedes-benz-e350/2010.md) | $9,437 | 105,733 | 67 |
| [2009](https://ottoquest.com/models/mercedes-benz-e350/2009.md) | $8,337 | 119,530 | 18 |
| [2008](https://ottoquest.com/models/mercedes-benz-e350/2008.md) | $7,276 | 124,259 | 34 |
| [2007](https://ottoquest.com/models/mercedes-benz-e350/2007.md) | $6,910 | 110,195 | 36 |
| [2006](https://ottoquest.com/models/mercedes-benz-e350/2006.md) | $6,152 | 122,252 | 19 |

## Recalls · 12

NHTSA, this model year.

- FUEL SYSTEM, GASOLINE:DELIVERY:FUEL PUMP (Jun 26, 2023): Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles.  Please refer to MBUSA's recall report for specific vehicle details.  The fuel pump may shutdown, which can result in a loss of drive power.
- ELECTRICAL SYSTEM:SOFTWARE (May 20, 2022): Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles.  Please refer to MBUSA's recall report for specific vehicle model details.  An error in the communication module's SIM card software can cause a mobile network connection failure, disabling the emergency call (eCall) system.
- BACK OVER PREVENTION:DISPLAY FUNCTION (Apr 8, 2022): Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2018-2021 CLA-Class, GLE/GLS-Class, A-Class, C-Class, E-Class, E-Class Coupe/Convertible, GLA/GLB-Class, GLC-Class, and CLS-Class vehicles.  Please refer to MBUSA's recall report for specific vehicle model details.  The rearview camera may not display the rearview image due to a software error.  As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 111, "Rear Visibility."
- STEERING: STEERING WHEEL/HANDLE BAR (Mar 25, 2022): Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel.  Due to a software error in the hand detection control unit, the hands-off detection might not detect when the driver's hands are away from the steering wheel when using the Active Distance Assist DISTRONIC system.
- AIR BAGS:SENSOR:SIDE IMPACT (Jul 12, 2021): Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 CLS450, AMG E53, AMG CLS53, E350, E450, AMG GT43, AMG GT53, 2020 S450, S560, G550, AMG GLC63, 2020-2021 GLC300, and AMG G63 vehicles.  The side crash sensor connectors may come loose, which could delay the activation of air bags and seatbelts during a side impact crash.
- SEAT BELTS:REAR/OTHER:RETRACTOR (Jun 25, 2021): Mercedes-Benz, LLC (MBUSA) is recalling certain 2021 G550, AMG G63, E350, E450, AMG CLS53, AMG E53, AMG GT43, AMG GT53, AMG GT63, 2021-2022 CLS450, and AMG E63 vehicles.  The rear seat belt automatic locking retractors may deactivate early, which can prevent the child restraint system from securing properly.  As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 208, "Occupant Crash Protection."

## Used 2021 Mercedes-Benz E 350 prices: common questions

### What is a fair price for a used 2021 Mercedes-Benz E 350?

Used 2021 Mercedes-Benz E 350s for sale at U.S. dealers ask $29,391 on average (half ask less than $28,974), across 122 cars. The cars for sale have 49,918 miles on average: one with fewer miles is worth more, and one with more is worth less. To check one car's price against cars of its trim and mileage, enter its VIN in OttoQuest's free Deal Check.

### Where is a used 2021 Mercedes-Benz E 350 cheapest?

Among states with at least 10 for sale, Texas has the lowest average asking price, $26,905 across 14 cars with 55,989 miles on average, and Florida the highest, $29,206 across 14 with 42,901 miles on average. Part of a gap between states is mileage and trim, not the state.

### How long are used 2021 Mercedes-Benz E 350s for sale?

The 122 for sale with a listing date have been listed 63 days on average. A car listed much longer than that, or one whose price has already been cut, usually leaves more room to negotiate.

### How does the 2021 Mercedes-Benz E 350 compare with the 2020 and 2022?

The 2021 asks $29,391 on average with 49,918 miles; the 2020 asks $24,863 with 57,574 miles, and the 2022 asks $33,406 with 41,196 miles.

### Does the 2021 Mercedes-Benz E 350 have recalls?

NHTSA lists 12 safety recall campaigns that cover the 2021 Mercedes-Benz E 350. Repairs are free at a dealer of the make; check a car's VIN with NHTSA before you buy to see whether its recalls were fixed.

## More

- Check one car's price: https://ottoquest.com/deal-check.md?vin=<VIN>&price=<price>&mileage=<miles> (markdown; the page is https://ottoquest.com/deal-check)
- Value a car by model, trim, year and mileage: https://ottoquest.com/value
- Free alerts for new listings and price drops: https://ottoquest.com/deals

Used and certified cars for sale at U.S. dealers, each car counted once. Days listed are the dealer's own days on market where they publish it. Price moves compare the same cars at both ends of the window.

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OttoQuest · [this page](https://ottoquest.com/models/mercedes-benz-e350/2021). Prices are asking prices of cars for sale in the U.S. and recorded sold prices; a guide to the price, not to a car's condition.