The average asking price for a used 2021 Mercedes-Benz CLS 450 is $38,846, with 45,701 miles on average, across 28 cars for sale at U.S. dealers as of Nov 10, 2026.
| State | Average asking | Average miles | For sale | Days listed |
|---|---|---|---|---|
| Florida | $37,650 | 53,525 | 6 | 35 |
Used 2021 Mercedes-Benz CLS 450s for sale at U.S. dealers ask $38,846 on average (half ask less than $39,906), across 28 cars. The cars for sale have 45,701 miles on average: one with fewer miles is worth more, and one with more is worth less. To check one car's price against cars of its trim and mileage, enter its VIN in OttoQuest's free Deal Check.
The 25 for sale with a listing date have been listed 37 days on average. A car listed much longer than that, or one whose price has already been cut, usually leaves more room to negotiate.
The 2021 asks $38,846 on average with 45,701 miles; the 2020 asks $32,669 with 58,113 miles, and the 2022 asks $43,432 with 34,984 miles.
NHTSA lists 8 safety recall campaigns that cover the 2021 Mercedes-Benz CLS 450. Repairs are free at a dealer of the make; check a car's VIN with NHTSA before you buy to see whether its recalls were fixed.
Used and certified cars for sale at US dealers, each car counted once. Days listed are the dealer’s own days on market where they publish it. Price moves compare the same cars at both ends of the window.
