The average asking price for a used 2021 Mercedes-Benz E 53 AMG is $44,809, with 54,079 miles on average, across 18 cars for sale at U.S. dealers as of Nov 10, 2026.
Used 2021 Mercedes-Benz E 53 AMGs for sale at U.S. dealers ask $44,809 on average (half ask less than $45,317), across 18 cars. The cars for sale have 54,079 miles on average: one with fewer miles is worth more, and one with more is worth less. To check one car's price against cars of its trim and mileage, enter its VIN in OttoQuest's free Deal Check.
The 18 for sale with a listing date have been listed 32 days on average. A car listed much longer than that, or one whose price has already been cut, usually leaves more room to negotiate.
The 2021 asks $44,809 on average with 54,079 miles; the 2020 asks $40,394 with 48,807 miles, and the 2022 asks $50,561 with 42,525 miles.
Used and certified cars for sale at US dealers, each car counted once. Days listed are the dealer’s own days on market where they publish it. Price moves compare the same cars at both ends of the window.
