The average asking price for a used 2022 Mercedes-Benz S 500 is $58,695, with 34,041 miles on average, across 4 cars for sale at U.S. dealers as of Nov 10, 2026.
Used 2022 Mercedes-Benz S 500s for sale at U.S. dealers ask $58,695 on average (half ask less than $59,392), across 4 cars. The cars for sale have 34,041 miles on average: one with fewer miles is worth more, and one with more is worth less. To check one car's price against cars of its trim and mileage, enter its VIN in OttoQuest's free Deal Check.
The 2022 asks $58,695 on average with 34,041 miles; the 2023 asks $65,991 with 29,672 miles.
NHTSA lists 9 safety recall campaigns that cover the 2022 Mercedes-Benz S 500. Repairs are free at a dealer of the make; check a car's VIN with NHTSA before you buy to see whether its recalls were fixed.
Used and certified cars for sale at US dealers, each car counted once. Days listed are the dealer’s own days on market where they publish it. Price moves compare the same cars at both ends of the window.