The average asking price for a used 2022 Mercedes-Benz E 450 is $44,373, with 38,952 miles on average, across 78 cars for sale at U.S. dealers as of Nov 10, 2026.
| State | Average asking | Average miles | For sale | Days listed |
|---|---|---|---|---|
| Florida | $46,599 | 38,759 | 19 | 46 |
| California | $42,451 | 41,387 | 10 | 60 |
| Texas | $43,052 | 33,731 | 7 | 55 |
| Illinois | $47,635 | 23,081 | 5 | 39 |
Used 2022 Mercedes-Benz E 450s for sale at U.S. dealers ask $44,373 on average (half ask less than $43,145), across 78 cars. The cars for sale have 38,952 miles on average: one with fewer miles is worth more, and one with more is worth less. To check one car's price against cars of its trim and mileage, enter its VIN in OttoQuest's free Deal Check.
The 78 for sale with a listing date have been listed 52 days on average. A car listed much longer than that, or one whose price has already been cut, usually leaves more room to negotiate.
The 2022 asks $44,373 on average with 38,952 miles; the 2021 asks $39,488 with 44,355 miles, and the 2023 asks $54,111 with 24,775 miles.
NHTSA lists 5 safety recall campaigns that cover the 2022 Mercedes-Benz E 450. Repairs are free at a dealer of the make; check a car's VIN with NHTSA before you buy to see whether its recalls were fixed.
Used and certified cars for sale at US dealers, each car counted once. Days listed are the dealer’s own days on market where they publish it. Price moves compare the same cars at both ends of the window.
| 2023 | $54,111 | 24,775 | 229 |
| 2022 | $44,373 | 38,952 | 78 |
| 2021 | $39,488 | 44,355 | 49 |
| 2020 | $31,549 | 58,700 | 69 |
| 2019 | $28,965 | 63,909 | 82 |
